助教
名前
白神 ウォルター 慧一郎
出身地
カリフォルニア州ロサンゼルス生まれ,神戸育ち
研究テーマ
テラヘルツ分光法を用いた細胞内のピコ秒/サブピコ秒における水の動態評価

 

受賞歴
2020年1月13日 Poster Award (Biology Prize),"Characterization of physical properties of water engaged in barrier function of the stratum corneum in the skin epidermis",FY2019 SPDR Presentation of Research Results
2016年11月24日 最優秀若手講演賞,"二糖水溶液中の水和状態及び水素結合ネットワーク破壊の定量評価",シンポジウム テラヘルツ科学の最先端V
2015年11月21日 最優秀発表賞,"タンパク質表層における水の動的・構造的特性の評価",シンポジウム テラヘルツ科学の最先端II
2013年10月30日 ポスター奨励賞,"テラヘルツ帯の誘電特性に基づく細胞中の水ダイナミクス評価",テラヘルツ分光法の最先端V ~どこへ行くテラヘルツ分光~
2013年4月25日 Student Best Presentation Award SeTBio'13,"Evaluation of the Hydration Effect of Monosaccharides in the THz Region",The 1st International Conference on Sensing Technologies for Biomaterial, Food and Agriculture 2013 (SeTBio)
2012年11月28日 FTT Student Best Presentation Award,"Development of the Cell Measuring System based on THz TD-ATR Spectroscopy",International Symposium on Frontiers in THz Technology FTT2012
2012年8月12日 農業機械学会関西支部学生ベストプレゼンテーション賞,"Evaluation of Optical Properties on Living Cells in Terahertz Region",農業機械学会関西支部第128回例会
2011年12月24日 ABEベストプレゼンテーション賞,"細胞計測のためのATR-THz分光装置における基礎研究",第12回計測自動制御学会システムインテグレーション部門講演会

 

原著論文(第一著者)
(18) K. Shiraga, S. Chen, M. Morita, " Hydration water as a primary factor in the moisture absorption of polyols: Insights from microscopic understanding at the molecular level", Journal of Molecular Liquids, 414(A), pp. 125988, (2024).
(17) K. Shiraga, Y. Ogawa, S. Kikuchi, M. Amagai,T. Matsui, "Increase in the Intracellular Bulk Water Content in the Early Phase of Cell Death of Keratinocytes, Corneoptosis, as Revealed by 65 GHz Near-Field CMOS Dielectric Sensor", Molecules, 27(9), pp. 2886, (2022).
(16) K. Shiraga, Y. Fujii, A. Koreeda, K. Tanaka, T. Arikawa, Y. Ogawa, "Dynamical collectivity and nuclear quantum effects on the intermolecular stretching mode of liquid water", The Journal of Physical Chemistry B, 125(6), pp. 1632-1639, (2021).
【Featured on the Journal Cover】
(15) K. Shiraga, M. Urabe, T. Matsui, S. Kikuchi and Y. Ogawa, "Highly precise characterization of the hydration state upon thermal denaturation of human serum albumin using a 65 GHz dielectric sensor", Physical Chemistry Chemical Physics, 22(35), pp. 19468-19479, (2020).
【Featured on the Journal Cover】
(14) K. Shiraga, K. Tanaka, T. Arikawa, S. Saito and Y. Ogawa, "Reconsideration of the relaxational and vibrational line shapes of liquid water based on ultrabroadband dielectric spectroscopy", Physical Chemistry Chemical Physics, 20(41), pp. 26200-26209, (2018).
(13) K. Shiraga, Y. Ogawa, K. Tanaka, T. Arikawa, N. Yoshikawa, M. Nakamura, K. Ajito and T. Tajima, "Coexistence of kosmotropic and chaotropic impacts of urea on water as revealed by terahertz spectroscopy", The Journal of Physical Chemistry B, 122(3), pp. 1268-1277, (2018).
(12) K. Shiraga, A. Adachi and Y. Ogawa, "Characterization of the hydrogen-bond network of water around sucrose and trehalose: H-O-H bending analysis", Chemical Physics Letters, 678, pp. 59-64, (2017)
(11) K. Shiraga, A. Adachi, M. Nakamura, T. Tajima, K. Ajito and Y. Ogawa, "Characterization of the hydrogen-bond network of water around sucrose and trehalose: Microwave and terahertz spectroscopic study", The Journal of Chemical Physics, 146(10), pp. 105102, (2017)
(10) K. Shiraga, Y. Ogawa and N. Kondo, "Hydrogen Bond Network of Water around Protein Investigated with Terahertz and Infrared Spectroscopy", Biophysical Journal, 111(12), pp. 2629-2641, (2016).
(9) K. Shiraga, T. Suzuki, N. Kondo, K. Tanaka and Y. Ogawa, "Hydration State inside HeLa Cell Monolayer investigated with Terahertz Spectroscopy", Applied Physics Letters, 106(25), pp. 253701, (2015).
(8) K. Shiraga, T. Suzuki, N. Kondo, T. Tajima, M. Nakamura, H. Togo, A. Hirata, K. Ajito and Y. Ogawa, "Broadband Dielectric Spectroscopy of Glucose Aqueous Solution: Analysis of the Hydration State and the Hydrogen Bond Network", The Journal of Chemical Physics, 142(23), pp. 234504, (2015).
(7) K. Shiraga, H. Naito, T. Suzuki, N. Kondo and Y. Ogawa, "Hydration and Hydrogen Bond Network of Water during the Coil-to-Globule Transition in Poly(N-isopropylacrylamide) Aqueous Solution at Could Point Temperature", The Journal of Physical Chemistry B, 119(17), pp. 5576-5587, (2015).
(6) K. Shiraga, T. Suzuki, N. Kondo, J. De Baedemaeer and Y. Ogawa, "Quantitative Characterization of Hydration State and Destructuring Effect of Monosaccharides and Disaccharides on Water Hydrogen Bond Network", 406, pp. 46-54, (2015).
(5) K. Shiraga, T. Sukuzi, N. Kondo and Y. Ogawa, "Hydration and Hydrogen Bond Network of Water around Hydrophobic Surface Investigated by Terahertz Spectroscopy", The Journal of Chemical Physics, 141(23), pp. 235103, (2014).
(4) K. Shiraga, Y. Ogawa, T. Suzuki, N. Kondo, A. Irisawa and M. Imamura, "Characterization of Dielectric Responses of Human Cancer Cells in the Terahertz Region", Journal of Infrared, Millimeters and Terahertz Waves, 35(5), pp. 493-302, (2014).
(3) K. Shiraga, Y. Ogawa, T. Suzuki, N. Kondo, A. Irisawa and M. Imamura, "Determination of the Complex Dielectric Constant of Cell Monolayer in Terahertz Region", Applied Physics Letters, 102(5), pp. 053702, (2013).
(2) K. Shiraga, Y. Ogawa, N. Kondo, A. Irisawa and M. Imamura,"Evaluation of the Hydration State of Saccharides using Terahertz Time-Domain Attenuated Total Reflection Spectroscopy", Food Chemistry, 140(1-2), pp. 315-320, (2013).
(1) 白神慧一郎,小川雄一,内藤啓貴,鈴木晢仁,冨田さくら,近藤直,”全反射減衰テラヘルツ分光法を用いた細胞の生存率推定”,計測自動制御学会論文集49(1),pp.197-202,(2013).

 

原著論文(共著者)
(20) H. Guo, Y. Cai, Y. Ogawa, K. Shiraga, N. Kondo, Y. Ogawa, "Quantification of resistant starch content in rice after hydrothermal treatments using terahertz spectroscopy", Food Research International, 186, pp. 114400, (2024).
(19) H. Guo, K. Shiraga, N. Kondo, S. Chen, Y. Yamashige, Y. Ogawa, "Determining changes in crystallinity of rice starch after heat-moisture treatment using terahertz spectroscopy", Food Chemistry, 425, pp. 136237, (2023).
(18) Siyao Chen, Yoshihisa Yamashige, Takeshi Mitsunaka, Naoshi Kondo, Keiichiro Shiraga, Yuichi Ogawa, "Dielectrophoresis-assisted 65-GHz LC-oscillator array CMOS chips for label-free and sensitive detection of microorganism cells", Sensors and Actuators A: Physical, 354, pp. 114286, (2023).
(17) L. W. Jacky Tsay, S. Tomoo, Z. Huang, H. Nakanishi, T. Suzuki, K. Shiraga, Y. Ogawa, N. Kondo, "An acoustic based local positioning system for dynamic UAV in GPS-denied environments", Applied Engineering in Agriculture 39(3), pp. 315-323, (2023).
(16) M. Morita, F. Matsumura, T. Shikata, Y. Ogawa, N. Kondo, K. Shiraga, "Hydrogen-bond configurations of hydration water around glycerol investigated by HOH bending and OH stretching analysis", The Journal of Physical Chemistry B, 126(47), pp. 9871-9880, (2022).
【Featured on the Journal Cover】
(15) L. W. Jacky Tsay, T. Shiigi, X. Zhao, Z. Huang, K. Shiraga, T. Suzuki, Y. Ogawa, N. Kondo, "Static and dynamic evaluations of acoustic positioning system using TDMA and FDMA for robots operating in a greenhouse", International Journal of Agricultural and B
(14) H. Tamura, T. Shiigi, T. Nisizu, H. Yoshitomi, S. N. Njane, K. Ogata, K. A. Omwange, K. Shiraga, T. Suzuki, Y. Ogawa, N Kondo, "Fish volume estimation and accuracy of multiple-neck underwater Helmholtz resonators", Journal of the Japanese Society of Agricultural Machinery and Food Engineers, 84(30, pp. 155-165, (2022).
(13) K. A. Omwange, Y. Saito, D. F. A. Riza, H. Zichen, M. Kuramoto, K. Shiraga, Y. Ogawa, N. Kondo, T. Suzuki, "Japanese dace (Tribolodon hakonensis) fish freshness estimation using front-face fluorescence spectroscopy coupled with chemometric analysis", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 276, pp. 121209, (2022).
(12) K. A. Omwange, D. F. A. Riza, Y. Saito, T. Suzuki, Y. Ogawa, K. Shiraga, F. Giametta and N. Kondo, "Potential of front face fluorescence spectroscopy and fluorescence imaging in discriminating adulterated extra-virgin olive oil with virgin olive oil", Food Control, 124, pp. 107906, (2021).
(11) T. Matsui, N. Kadono-Maekubo, Y. Suzuki, Y. Furuichi, K. Shiraga, ..., A. Miyawaki and M. Amagai, "A unique mode of keratinocyte death requires intracellular acidification", Proceedings of the National Academy of Sciences, 118(17), pp. e2020722118, (2021).
(10) Y. Ogawa, S. Kikuchi, Y. Yamashige, K. Shiraga and T. Mitsunaka, "Near-field sensor array with 65-GHz CMOS oscillators for rapid detection of viable Escherichia coli", Biosensors and Bioelectronics, 176, pp. 112935, (2020).
(9) S. Nakajima, K. Shiraga, T. Suzuki, N. Kondo and Y. Ogawa, "Quantification of starch content in germinating mung bean seedlings by terahertz spectroscopy", Food Chemistry, 294, pp. 203-208, (2019).
(8) K. Usui, N. Kadono, Y. Furuichi, K. Shiraga, T. Saitou, H. Kawasaki, K. Toyooka, H. Tamura, A. Kubo, M. Amagai and T. Matsui, "3D in vivo imaging of the keratin filament network in the mouse stratum granulosum reveals profilaggrin-dependent regulation of keratin bundling", Journal of Dermatological Science, 94(3), pp. 346-349, (2019).
(7) M. Morita, M. Kanayama, K. Shiraga, T. Suzuki and Y. Ogawa, "Water content of human stratum corneum measured in vivo by terahertz attenuated total reflection spectroscopy: Influence of moisturization", IFSCC Magazine, 2, pp. 39-44, (2018).
(6) K. Otake, N. Sato, A. Kitaguchi, T. Irahara, S. Murata, K. Shiraga, Y. Ogawa, T. K. Fujiwara, K. Koike and H. Yokota, "The effect of lactoferrin and pepsin-treated lactoferrin on IEC-6 cell damage induced by clostridium difficile toxin B", Shock, 50(1), pp.119-125, (2018).
(5) S. Nakajima, K. Shiraga, T. Suzuki, N. Kondo and Y. Ogawa, "Chlorophyll, carotenoid and anthocyanin accumulation in mung bean seedling under clinorotation", Microgravity Science and Technology, 29(6), pp. 427-432, (2017).
(4) 上田義勝,徳田陽明,二瓶直登,杉山暁史,小川雄一,白神慧一郎,"微細気泡水の電気化学的特性の定量評価及び応用実験との相関について",日本混相流学会28(5),pp. 555-562,(2015).
(3) F. Miyamau, K. Hattori, K. Shiraga, S. Kawashima, S. Suga, T. Nishida, M. W. Takeda and Y. Ogawa, "Highly Sensitive Terahertz Sensing of Glycerol-Water Mixtures with Metamaterials", Journal of Infrared, Millimeter and Terahertz Waves, 35(2), pp. 198-207, (2014).
(2) S. Tanaka, K. Shiraga, Y. Ogawa, Y. Fujii, S. Okamura, "Effect of Pore Conformation on Dielectric Anisotropy of Oven-Dry Wood Evaluated using Terahertz Time-Domain Spectroscopy and Eigenvalue Problems for Two-Dimensional Photonic Crystals", Journal of Wood Science, 60(3), pp. 194-200, (2014).
(1) S. Tanaka, K. Shiraga, Y. Ogawa, Y. Fujii, S. Okamura, "Applicability of Effective Medium Theory to Wood Density Measurements using Terahertz Time-Domain Spectroscopy", Journal of Wood Science, 60(2), pp. 111-116, (2014).

 

解説記事
(6) 白神慧一郎, "超広帯域誘電分光で観る水の誘電緩和ダイナミクス", 分光研究, 72(6), pp. 227-230, (2024).
(5) 白神慧一郎,小川雄一,"水の質から生命現象を切り拓く新技術",化学工業,72(8),pp. 571-576,(2021).
(4) 小川雄一,白神慧一郎,"テラヘルツ分光法による細胞内水分子ダイナミクスの評価",光学,48(10),PP.419-424,(2019).
(3) 白神慧一郎, "テラヘルツ帯における水のスペクトル解析", OPTRONICS, 38(5), pp. 84-88, (2019).
(2) 白神慧一郎,足立絢,小川雄一,"糖ー水の相互作用による耐凍結乾燥特性の究明",冷凍,90(1051),p.26-31,(2015).
(1) 小川雄一,白神慧一郎,"テラヘルツ波帯における生細胞の複素誘電率計測",化学工業,64(11),pp. 14-19,(2013).
特許等

特許公開公報

(3) 白神慧一郎,松井毅,菊池正二郎,澤田美香,小川雄一,鈴木哲仁: テラヘルツ波を用いた細胞評価用の媒質 (特願2017-183305,特開2019-60609),出願日2017年9月22日.
(2) 田島卓郎,小川雄一,白神慧一郎: 誘電分光装置 (特願2016-084972, 特開2017-194361),出願日2016年4月21日.
(1) 小川雄一,白神慧一郎,赤宗行三,森田美穂,土田克彦: 水分量測定方法 (特願2014-179671, 特開2016-53527),出願日2014年9月3日.

特許公報

(2) 田島卓郎,小川雄一,白神慧一郎: 誘電分光装置 (特願2016-084972, 特開2017-194361),出願日2016年4月21日.
(1) 小川雄一,白神慧一郎,赤宗行三,森田美穂,土田克彦: 水分量測定方法 (特願2014-179671, 特開2016-53527),出願日2014年9月3日.